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Darwin
Senior User
Joined: 11 Feb 2008
Posts: 109
Location: Perth, Western Australia
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 Posted: Sat Aug 16, 2008 10:46 am Post subject: SIRT and MAX |
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Hello Everyone
Firstly an update - My ex is currently having 25 treatments of radiation to the pelvic area over a five week period for a tumour that is in his sacro spineal notch area and this was causing great pain when he tried to stand or walk. The treatment is at the same time as a low dosage 5FU plus Avastin given 24?7 by pump. The side effects are rather uncomfortable for him but today he was able to walk for about 20 minutes and walk up some steps so that is a huge imporvement.
After he finishes this treatment he will have a week or so with no treatment to let his body rest and then he is going to have radioactive spheres injected into his liver they are called SIRT. I can't seem to find much on the success rate of these spheres or how long they give you before the tumour start regrowing.. They are not a cure but shrink the tumors in the liver which are mets from his bowel cancer.
After this treatment his Oncologist wants to try him on a new chemo cocktail called MAX has anyone heard of this and if so what can you tell me about this. The dr said he has had patients live for a number of years on this MAX chemo.
My thoughts and prayers are with you all. Thanks in advance for any info you would like to share.
D
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Ex husband's diagnosis was January 2006, stage IV bowel cancer with mets to liver and lungs. Two years of continuous chemo, folfox then folfirri. On MAX chemo now. Has had radiation to pelvic area and radioactive SIRT spheres injected through the portal vein into the liver. |
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brainman
Site Admin
Joined: 13 Oct 2005
Posts: 4209
Location: Tennessee
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| Posted: Sat Aug 16, 2008 2:20 pm Post subject: Re: SIRT and MAX |
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Hi Dorothy. I think MAX is a cocktail of Mitomycin C, Avastin and Xeloda. All are know chemotherapy agents. Since I never used any of them, I do not have any personal experience with them. An excellent source of information on medications is http://www.rxlist.com/script/main/hp.asp . I look there often when looking for info on prescription medications. It is rather comprehensive. Hope it help you and John.
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Jim
Site Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendoglioma grade 3, same location.
My Story Part 1: http://cancerforums.net/viewtopic.php?p=7350
My Story Part 2: http://cancerforums.net/viewtopic.php?t=8029
Blog http://jimhawkinsport.blogspot.com/ |
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Darwin
Senior User
Joined: 11 Feb 2008
Posts: 109
Location: Perth, Western Australia
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| Posted: Sat Aug 16, 2008 7:32 pm Post subject: Re: SIRT and MAX |
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Thanks Jim I wioll save this reference. Do they come under any other names as these don't seem to be on that list.
Hope all is well with you
Dorothy
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Ex husband's diagnosis was January 2006, stage IV bowel cancer with mets to liver and lungs. Two years of continuous chemo, folfox then folfirri. On MAX chemo now. Has had radiation to pelvic area and radioactive SIRT spheres injected through the portal vein into the liver. |
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brainman
Site Admin
Joined: 13 Oct 2005
Posts: 4209
Location: Tennessee
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| Posted: Sat Aug 16, 2008 9:03 pm Post subject: Re: SIRT and MAX |
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Avastin = Generic name Bevacizumab
Mitomycin = Brand name Mutamycin
Xeloda = Generic name Caperitabine
All six names are listed on that site. I have heard about Avastin and Xeloda before but not about Mitomycin.
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Jim
Site Administrator and long-term cancer survivor
1992 Astrocytoma grade 2, left motor strip
2005 Recurrence this time said to be an Oligodendoglioma grade 3, same location.
My Story Part 1: http://cancerforums.net/viewtopic.php?p=7350
My Story Part 2: http://cancerforums.net/viewtopic.php?t=8029
Blog http://jimhawkinsport.blogspot.com/ |
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Darwin
Senior User
Joined: 11 Feb 2008
Posts: 109
Location: Perth, Western Australia
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| Posted: Sat Aug 16, 2008 10:47 pm Post subject: Re: SIRT and MAX |
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WOW!!! Jim you really are a wealth of information. I am IMPRESSED!!!
Shouldn't you be sleeping:)
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Ex husband's diagnosis was January 2006, stage IV bowel cancer with mets to liver and lungs. Two years of continuous chemo, folfox then folfirri. On MAX chemo now. Has had radiation to pelvic area and radioactive SIRT spheres injected through the portal vein into the liver. |
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brainman
Site Admin
Joined: 13 Oct 2005
Posts: 4209
Location: Tennessee
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DulcimerGal
Senior User
Joined: 01 Apr 2008
Posts: 114
Location: Virginia
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| Posted: Mon Aug 18, 2008 4:33 pm Post subject: Re: SIRT and MAX |
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Great to see your update on John - I am so pleased to hear he is hanging in there and that you guys are still actively seeking new treatments!
Looks like this was a good move for both of you Dorothy - you are a wonderful support for him. I am so appreciating my husband right now - he has driven me everywhere and done so much to help me.....I am sure John feels the same way about you -
Good luck and prayers for you both
DulcimerGal
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Rectal Cancer diagnosed Valentines Day 2008
Finished 6 weeks of radiation and chemo 4/23/08
Surgery to remove tumor - June 18th 2008
Colostomy Reversal August 20th 2008
Five rounds of Xeloda (chemo) to ZAP anything left! |
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