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PUMA protein coordinates the cell-suicide activities of p53 What is this ?

 
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leo
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Joined: 23 Sep 2004
Posts: 1574
PostPosted: Thu Sep 08, 2005 3:07 pm    Post subject: PUMA protein coordinates the cell-suicide activities of p53 Reply with quote
The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital. A report on this work appears in the September 9 issue of Science.

[url=http://www.eurekalert.org/pub_releases/2005-09/sjcr-ppc090805.php]Read more...[/url]
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mikes
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Joined: 25 Jul 2005
Posts: 143
PostPosted: Thu Sep 08, 2005 11:32 pm    Post subject: Re: PUMA protein coordinates the cell-suicide activities of p53 Reply with quote
HI leo,

I am especially interested in this news item.

I noticed that a Google for 'p53 Bcl-xL PUMA psk cancer' or
'p53 Bcl-xL PUMA melatonin cancer' both turn up a fair amount of articles.

Most of the promising ones wind up on a page where you have to pay for the article.

Without being sure what some of these articles say (especially the ones I can't get), it looks like they may be explaining how melatonin and psk affect these critical genes and actually work.

Thank you so much for this post.

Mike
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